What is Lynch Syndrome?

Lynch Syndrome is a hereditary disorder caused by a mutation in a mismatch repair gene in which affected individuals have a higher than normal chance of developing colorectal cancer, endometrial cancer, and various other types of aggressive cancers, often at a young age – also called hereditary nonpolyposis colon cancer (HNPCC).

Children of a Lynch syndrome parent possess a 50% risk of acquiring a mutation.  Those with Lynch syndrome carry up to an 85% risk of contracting colon cancer as well as a higher than average risk for endometrial cancer, stomach, pancreas, kidney/ureter tract, hepatobiliary tract, gastric tract, prostate, ovarian, gallbladder duct, brain, small intestine, common breast and skin cancers.  Lynch Syndrome is not a rare condition but rather an  under-diagnosed one!

Our Open Access nurses at Regional Gi ask our patients specific questions to identify patients at risk and refer them to genetic counselors for further investigation to determine if the patient or their family requires genetic testing for Lynch Syndrome.

For information on Lynch Syndrome, visit Lynch Syndrome International at http://lynchcancers.com/.